Dr. Ioana Roman

Dr. Ioana Roman

Scientific researcher III
INSTITUTE OF BIOLOGICAL RESEARCH – ICB Cluj-Napoca

My research directions are complex, focusing mainly on endocrine-immune correlations. Since 2013, I have dedicated myself to pharmacological and toxicological studies on vertebrates, using biochemical and hematological methods.

Email

ioana.roman@icbcluj.ro

  • REASEARCH
  • PROJECTS
  • PUBLICATIONS
I am a researcher with expertise in preclinical, toxicological studies, biological sample processing services. My research involves: 
  • Bioequivalence studies: - preclinical for newly synthesized and/or derivatized pharmaceutical compounds; - testing new plant extracts with phytotherapeutic potential.
 
  • Toxicity studies: evaluation of the action of pollutants on animal metabolism; the industry of preservatives, pesticides, medicines;
 
  • Laboratory processing services of biological samples, respectively: serum, plasma and other biological fluids as well as tissues, for scientific, pharmacological and biotechnological purposes, based on work protocols well established by the beneficiary.
 
    • 1999 – 2001, Grant ANSTI, type T: Research on the effects of some glucocorticoids on some endocrine-metabolic and immunobiological processes and the role of alpha-hydroxy acids in mitigating these effects.
     
    • 2012-2015, theme 202, BIODIV: Morphophysiological, phytocoenological, biochemical, histochemical (histoenzymological) studies on some species of officinal plants rich in active principles in order to obtain phytopharmaceutical biopreparations.
     
    • Project: POCU/626/6/13/130631: „Practice for a sustainable development” – Practice tutor, during the period 01-31.07.2021 and 15.12.2021 – 15.01.2022.
    • Roman I., Moldoveanu CA, Drăgan Ș, Baumi J, Cimpoiu C, Toma V-Al, Neurotrophic effects of iridoid glycosides from Lamium album l. as natural glp1-r modulators in repeated restraint stress. Studia UBB Chemia, LXIX (3): 35-53. DOI:10.24193/subbchem.2024.3.03
     
    • Stoica AD, Sevastre B, Suciu M, Pârvu AE, Pârvu M, Toma VA, Roman I, Dobre C, 2023. Chemoprotective Effect of Plantago sempervirens Crantz Extract on Ovarian Structure and Folliculogenesis. Sci. 2023, 13, 3134. https://doi.org/10.3390/ app13053134
     
    • Stoica AD, Toma V-Al, Roman I, Sevastre B, Scurtu F, Silaghi-Dumitrescu R, 2022. Glutaraldehyde-Polymerized Hemerythrin: Evaluation of Performance as an Oxygen Carrier in Hemorrhage Models, Bioinorganic Chemistry and Applications, vol. 2022: 2209101. https://doi.org /10.1155 /2022/2209101.
     
    • Racz LZ, Racz CP, Pop LC, Tomoaia G, Mocanu A, Barbu I, Sárközi M, Roman I, Avram A, Tomoaia-Cotisel M, Toma V-Al, 2022. Strategies for Improving Bioavailability, Bioactivity, and Physical-Chemical Behavior of Curcumin. Molecules, 27: 6854. https://doi.org/10.3390/ molecules27206854.
     
    • Farcas AD, Toma V-Al, Roman I, Sevastre B, Scurtu F, Silaghi-Dumitrescu R, 2020. Glutaraldehyde-Polymerized Hemoglobin: In Search of Improved Performance as Oxygen Carrier in Hemorrhage Models. Bioinorganic Chemistry and Applications, 2020: 1096573. https://doi.org/10.1155 /2020 /1096573.
     
    • Farcas AD, Mot AC, Zagrean-Tuza C, Toma V, Cimpoiu C, Hosu A, Pârvu M, Roman I*, Radu Silaghi-Dumitrescu, 2018. Chemo-mapping and biochemical-modulatory and antioxidant/prooxidant effect of Galium verum extract during acute restraint and dark stress in female rats. PLoS ONE, 13(7): e0200022. https://doi.org/10.1371/journal.pone.0200022
     
    • Ioana Roman, Anca Farcaș, Vlad Al. Toma, 2017. Effect of Lingonberry Extracts on Blood Pressure and Myocardium in Paracetamol Intoxication. Bulletin UASVM Veterinary Medicine, 74(1), 118-122. https://doi.org/10.15835/buasvmcn-vm:12626
     Books
    • RUSU MA., Tămaş M, ROMAN I, 2007. PRODUSE FITOTERAPEUTICE TESTATE ÎN TOXICOZE HEPATICE EXPERIMENTALE. Edit. TODESCO, Cluj-Napoca, 258 pag., ISBN: 978-973-7695-30-7

We explore life, discovering solutions for a sustainable future.